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Soy Supplements for Menopausal Symptoms: Higher Doses and More Frequent Dosing May Help

Soy Supplements for Menopausal Symptoms: Higher Doses and More Frequent Dosing May Help

Studies assessing the effectiveness of complementary and alternative medicines (CAM) for the treatment of menopause-related hot flashes have yielded conflicting results.  Most studies have demonstrated that treatments such as soy and black cohosh are not likely to be effective in most women; however, a new study suggests that women who take higher doses (100 to 200 mg)of isoflavones and more frequent dosing (2-3 times per day) may experience a greater reduction in the frequency of hot flashes.

Ruta Nonacs, MD PhD

Crawford SL, Jackson EA, Churchill L, et al.Impact of dose, frequency of administration, and equol production on efficacy of isoflavones for menopausal hot flashes: a pilot randomized trial.Menopause, May 2013.

Reviewed in Medscape

Atypical Antipsychotic Medications: What Do We Know About Their Reproductive Safety?

Atypical Antipsychotic Medications: What Do We Know About Their Reproductive Safety?

Atypical antipsychotic medications are commonly used for the treatment of schizophrenia and bipolar disorder.  Despite the increasing use of these medications in women of child-bearing age, there is still relatively ...

New Research from the CWMH: Vasomotor Symptoms Frequently Recur After Discontinuation of SSRI

New Research from the CWMH: Vasomotor Symptoms Frequently Recur After Discontinuation of SSRI

For the treatment of menopausal vasomotor symptoms (VMS), such as hot flashes and night sweats, selective serotonin reuptake inhibitors (SSRIs) are effective and well-tolerated.  Positive effects are observed within 4 ...

Remote Enrollment Initiated in MGH Study Assessing Mood Symptoms Across Infertility Treatment

Remote Enrollment Initiated in MGH Study Assessing Mood Symptoms Across Infertility Treatment

We are pleased to announce the recent launch of an exciting new research initiative that is being conducted by the Massachusetts General Hospital Center for Women’s Mental Health.  The Symptom ...

Omega-3 Fatty Acids and Perinatal Depression: Maybe or Maybe Not

Omega-3 Fatty Acids and Perinatal Depression: Maybe or Maybe Not

The omega-3 fatty acids, including eicosapentaenoic acid (EPA) and docosahexanoic acid (DHA), have a broad range of health benefits and may be beneficial for the treatment of mood disorders.  Because ...

Mediterranean Diet Benefits Perimenopausal Women with Hot Flashes

Mediterranean Diet Benefits Perimenopausal Women with Hot Flashes

In a large study from Australia, researchers found that menopausal women who ate diets high in fruit, certain vegetables, pasta and red wine were 20% less likely to have ...

Research from the CWMH: Duloxetine for Menopausal Symptoms

Research from the CWMH: Duloxetine for Menopausal Symptoms

A substantial proportion of women transitioning into menopause experience a new onset or recurrence of depressive symptoms.  A new study from the Center for Women’s Mental Health indicates that ...

SSRI Exposure During Pregnancy Does Not Appear to Affect Infant Growth

SSRI Exposure During Pregnancy Does Not Appear to Affect Infant Growth

Some studies have shown an association between in utero exposure to antidepressants and various pregnancy outcomes, including preterm delivery, low birth weight, and lower Apgar scores; however, these outcomes have ...

Gabapentin (Neurontin) and Pregnancy

Gabapentin (Neurontin) and Pregnancy

Despite the fact that gabapentin (Neurontin) is now used in a wide variety of clinical settings -- for epilepsy, pain management, anxiety, sleep disturbance – there is relatively little information ...

FDA Announces Approval of a New (Old) Medication for Nausea and Vomiting in Pregnancy

FDA Announces Approval of a New (Old) Medication for Nausea and Vomiting in Pregnancy

The combination of doxylamine succinate and pyridoxine hydrochloride (vitamin B6), to be marketed as Diclegis, has been approved by the FDA for the treatment of nausea and vomiting in ...