To sign up for future studies, please submit the Research Registry form below
We are currently enrolling patients for the following research studies:
1. BIPOLAR DISORDER IN PREGNANCY
Are you an expectant mother?
Do you have questions about bipolar disorder and antidepressants or mood-stabilizers during pregnancy?
If you are pregnant and diagnosed with bipolar disorder (or manic depression), you may be eligible for this research study. Participants meet with research coordinators and psychiatrists who specialize in bipolar illness during pregnancy.
For more information about this study, please contact Rachel at (617) 726-2912 or rvanderkruik@partners.org.
2. TREATMENT OF PREMENSTRUAL WORSENING OF DEPRESSION
Seeking women between 18-45 with PMS who have been diagnosed with depression. If you are between 18 and 45 and:
- Suffer with PMS
- Currently being treated with an antidepressant
You may be eligible for a research study at Massachusetts General Hospital evaluating how a birth control pill helps with premenstrual mood symptoms. Women who participate will receive study medication and evaluations of their mood at no cost, and will be compensated up to $450.
For information, please call: (617) 724-6540 or email afarrell2@partners.org
3. MGH GENETICS UNIT: STUDY FOR CHILDREN EXPOSED TO VALPROIC ACID BEFORE BIRTH
The Genetics Unit of Massachusetts General Hospital is looking for children who were exposed to the anticonvulsant drug, valproate, before birth. There has been some concern that prenatal exposure to this drug increases the risk for Autism Spectrum Disorders (ASDs) in some children. We are studying whether the effects of exposure to valproate during pregnancy depend on the child’s genetic makeup (the presence of certain genes).
To participate in this study, the children must be at least 2 years of age. The research study would require only a one-day visit as an outpatient free of charge. For some children, the visit would be shorter than an entire day. Participants will receive $100 for his/her participation, and travel expenses will be reimbursed.
If you are interested in participating or would like more information, please contact Uma Deshmukh by calling 617-724-1252 or by e-mail at udeshmukh@partners.org. You can also call us at our toll-free number 1-866-354-1523
http://www.massgeneral.org/aed/valproate.htm
4. MGH PEDIATRIC PSYCHOPHARMACOLOGY: SEEKING FAMILIES TO PARTICIPATE IN A NEUROIMAGING STUDY OF RISK FOR MOOD DISORDERS
Do you have frequent mood swings? Do you go through times when you feel “too good,” overly excited or confident, overly active, or unusually irritable? Have you ever been diagnosed with mania or bipolar disorder? Do you have a child age 6-17 years?
If so, we would welcome your participation in our neuroimaging research study. This study looks at differences in brain chemicals among children who have a parent with bipolar disorder. We are interested in making sure that we have balanced representation of African American, Asian American and Latino families in our sample, so that our findings may help us learn about the community at large.
The study offers:
- Two brain scans (an MRI and an MRS scan) of your child at no cost
- An evaluation of your and your child’s emotional and behavioral functioning
- An evaluation of your child’s intellectual strengths and weaknesses
- Monetary compensation for you or your child for each assessment
- No treatment is provided in this study
Participation involves 2-3 study visits, each lasting 2-5 hours.
For more information, contact Caroline at (617) 503-1411.
5. MGH PEDIATRIC PSYCHOPHARMACOLOGY: DO YOU HAVE A CHILD AGE 2-5 YEARS?
Have you or your child’s other parent ever been diagnosed with Bipolar Disorder or mania?
Or, do you and your child’s other parent have no history of depression or mania?
If so, we would welcome your participation in our research study at the Massachusetts General Hospital, funded by the National Institutes of Health. We are looking at whether childhood temperamental characteristics can predict later behavior. We are interested in making sure that we have balanced representation of African American, Asian American and Latino families in our sample, so that our findings may help us to learn about the community at large.
The study offers:
- Yearly screenings of your child’s behavior at no cost
- A detailed behavioral and cognitive evaluation of your child at 6 years of age
- Monetary compensation for you or your child for each assessment
For more information, contact Marisa at (617) 503-1409 or see our web site at www.massgeneral.org/pediatricpsych (See Risk Factors for Adverse Outcome in Young Offspring of Bipolar Parents under Studies Currently Recruiting).



