The risk of depression after removal of both ovaries (also called bilateral oöphorectomy or surgical menopause) is a major factor for women to consider when they confront medical problems that require removal of the uterus (called a hysterectomy).  Many women are advised to consider having their ovaries removed when they are having the uterus removed.  [...]

Most obstetricians are now familiar with the potential for what has become known as neonatal distress syndrome (or “adaptation” syndrome) following third trimester exposure to SSRIs.  Some patients still worry about the possibility of their baby developing neonatal distress syndrome, especially if anything unusual happened during the post-delivery experience of an earlier pregnancy.  Women may [...]

A study published in the Archives of General Psychiatry shows that children of women who experience the death of a close relative may have an increased risk of developing schizophrenia later in life.  This study was conducted with records of children born in Denmark between 1973 and 1995, which were then linked to the central [...]

CYP3A4 is an intestinal enzyme that is part of the Cytochrome P450 metabolic system.  It is important in many drug-drug and drug-food interactions, and it is one of the first enzymes to break down medications when they enter the body. Grapefruit juice has been demonstrated to inhibit the functioning of CYP3A4 and its effect on [...]