Monthly Archives: June 2009


What Would You Do?  A Pregnant Women on Duloxetine (Cymbalta)

What Would You Do? A Pregnant Women on Duloxetine (Cymbalta)

Ms. A is a 27-year-old woman who is seven weeks pregnant and is currently taking duloxetine (Cymbalta).  She has a history of recurrent major depressive disorder (MDD) and has had a good response to duloxetine at 60 mg per day.  She has had four previous episodes of major depressive disorder (most untreated) and has been [...]

Do SSRIs Increase the Risk of Preeclampsia?

Do SSRIs Increase the Risk of Preeclampsia?

Hypertension in pregnancy is generally defined as a diastolic blood pressure of 90 mm Hg or greater or a systolic pressure at or above 140 mm Hg.  Preeclampsia is defined as the development of hypertension with proteinuria or edema induced by pregnancy, generally in the second half of gestation.  It is more common in women [...]

OCD in Pregnant and Postpartum Women

OCD in Pregnant and Postpartum Women

The lifetime prevalence rate of obsessive-compulsive disorder (OCD) has been consistently estimated to be 2%-3% in the general adult population throughout the world, making OCD one of more common psychiatric diagnoses; however research on OCD in pregnancy and peurperium has been limited. Although most studies have not been designed to estimate the prevalence of pregnancy-related [...]